Miguel Cabrera was asked last week how badly he wants to win the Triple Crown.

"You know," he said. "I'll leave that up to God."

Yes, well, Joe Mauer should have something to do with it, too, and the Twins catcher and Tigers third baseman will have a head-to-head matchup of sorts this weekend at Target Field.

The Twins and Tigers will hook up for the 2012 season's penultimate series with much on the line. Not only does first-place Detroit enter with a one-game lead on Chicago in the American League Central through Wednesday, Sept. 27, games, but Cabrera comes in as the front-runner in the American League MVP race and with the best chance to win the first major league Triple Crown in 45 years.