No matter who gets the snaps at quarterback for the Bills on Sunday – EJ Manuel or Jeff Tuel – the Patriots defense will have to be ready for a rookie who can run.

Just don’t count Tommy Kelly among those viewing Manuel as the next Michael Vick.

“He runs a little bit but he tries to stay in that pocket and get that ball out” said Kelly listed on the Patriots’ depth chart as a starting defensive tackle. “He’ll run when necessary but to say he’s like Michael Vick? No. But he’ll run he’s definitely a threat though.”

Manuel was the team’s first-round draft pick out of Florida State; Tuel is an undrafted rookie from Washington State. Tuel got more playing time during the preseason while Manuel has dealt with a knee injury – Kevin Kolb has been placed on injured reserve – but the Bills have named Manuel as the starter for Sunday’s opener in Buffalo.

Whoever is under center defensive end Rob Ninkovich said the defensive strategy is pretty similar.