The Knicks must be cursed.

The Knicks’ crisis went from bad to unthinkable Wednesday night. “The Melo Game’’ turned into a nightmare as center Tyson Chandler and Carmelo Anthony didn’t finish because of knee injuries as the lifeless Knicks were clobbered by the Nuggets, 117-94, at Pepsi Center .

The Knicks announced Chandler had a left knee contusion, and Anthony bolted early in the third quarter and will head back to New York to have his right knee drained and likely will miss the rest of the West Coast trip — if not more.

Coach Mike Woodson called Chandler “probable’’ for tonight against the Trail Blazers in Portland, but he was limping badly in the locker room, and Chandler said he was unsure of his status and has refused to take an X-ray.

Meanwhile, J.R. Smith afterward questioned the team’s “heart.’’

Anthony, booed during pregame introductions and even more vigorously when he handled the ball in the first half in his return to the building that was once his home court, was rattled, rusty and hobbled. He left the game early in the third quarter with his lingering sore right knee after going 3-of-12 for nine points — 0-of-5 from 3-point range — and getting beaten continuously on defense.”

“I just didn’t have it,’’ Anthony said. “I tried it. I think it was just time for me to give it some time and get to the bottom of it as soon as possible. It started tightening up. I felt I had no pop or power. I tried it in the second half and couldn’t move.’’