When White Sox designated hitter Dayan Viciedo knocked a home run 425 feet into the left-field stands against the Indians on Monday at U.S. Cellular Field, he provided teammate Jose Quintana with some needed relaxation on Memorial Day.

Viciedo's three-run homer allowed Quintana to pitch with the lead from the third inning, and the left-hander took advantage by earning his third victory of the season as the Sox topped the Indians 6-2.

Quintana improved to 3-0 against the Indians in nine career appearances, including seven starts, to help the Sox halt a two-game losing streak.

"I felt relaxed," Quintana said of his reaction to the home run. "I'm so happy with the support of runs. It was a close game."

Viciedo's fifth homer of the season — one of which was another three-run shot against the Indians — came with two outs after Marcus Semien reached on a fielding error and Conor Gillaspie singled. Viciedo also added a single and a run scored in the sixth, and Sox manager Robin Ventura said afterward that he has become a better hitter by working through his at-bats.

"It's a credit to the work," Viciedo said through a team interpreter. "It doesn't happen just like that. We've been working a lot, and I feel like the biggest thing is to make the adjustment. When you don't do good in one at-bat, then you come back and fix the problem. Concentration is one of the biggest things at-bat to at-bat, and having a plan."

Gillaspie continued his strong start by collecting a career-high four hits, including three doubles. His second double of the day led off the Sox's two-run sixth against Indians starter Josh Tomlin, and he also had an RBI double in the seventh. Gillaspie upped his batting average to a team-high .352.