Frank Francisco is hurting again.

The Mets reliever, on a rehab assignment for Class A St. Lucie, is scheduled to be examined by doctors this week after his elbow “didn’t feel very good” following a recent outing, according to manager Terry Collins.

Francisco, who underwent surgery in December to remove bone chips in his right elbow, hasn’t thrown a pitch for the Mets this season. But the team had considered activating him this weekend to provide bullpen depth.

“They thought he was making progress, ready to go to [Double-A] Binghamton and he just said he didn’t feel very good,” Collins said before the Mets’ 3-2 loss to the Pirates yesterday at Citi Field. “We did not have any date etched in stone that we knew he was coming.”

Francisco is making $6.5 million this season.

* Jeurys Familia was placed on the disabled list with right biceps tendinitis. Greg Burke was called up from Triple-A Las Vegas to fill Familia’s spot in the bullpen. Collins said the Mets might have tried to avoid a DL stint with Familia if the bullpen hadn’t been overextended Friday and Saturday because of abbreviated starts by Shaun Marcum and Jon Niese.