As far back as the NFL annual meetings in March Green Bay Packers coach Mike McCarthy had a plan in mind to improve his running game.

“You’d like to get into a one-two punch deal” McCarthy said.

As he talked at the Arizona Biltmore hotel back in March McCarthy had no way of knowing then what his roster would look like five months later but it was clear he envisioned one of those two punches would be thrown by DuJuan Harris. McCarthy liked how Harris finished last season when he started four games (including both playoff contests) and averaged 4.2 yards per carry with four touchdowns.

Even after the Packers drafted a pair of running backs -- Alabama’s Eddie Lacy in the second round and UCLA’s Johnathan Franklin in the fourth -- McCarthy continued to project Harris as his starter.

When Harris returned to practice Aug. 12 from the knee injury that kept him out for most of the offseason workouts McCarthy’s vision became more clear: He would use the quickness of the 5-foot-8 203-pound Harris and the power of Lacy (5-11 230) to provide that one-two punch to jolt a running game that finished 20th in the NFL last season.

Less than two weeks before the season opener at San Francisco McCarthy will be forced to alter that plan because Harris reinjured his knee in Friday’s preseason game against Seattle and is headed for injured reserve.

“It sucks honestly” left guard Josh Sitton said. “He’s a hell of a player. He was going to be a big part of this offense. You’ve got to move on.”

The Packers may have to ride Lacy who despite a rough outing against Seattle in which he totaled minus-5 yards rushing on eight attempts has been impressive so far.

“He’s going to have to step up and probably have a larger role” Sitton said. “He’s going to have to grow. He can’t be a rookie anymore.”

However there are concerns about Lacy’s conditioning and injury history that may prevent McCarthy from giving his rookie a greater workload than was originally planned.

“Every offseason you go through an evaluation with your offense you do offseason studies you project how you envision your offense looking and having to firm things up after the draft” McCarthy said Tuesday. “You have a vision of packages in place on how you’re going to start the season. That goes along with part of my individual focus for the season. So last week was the first opportunity to play both DuJuan and Eddie Lacy as a one-two punch format.”

Because Franklin doesn’t look ready to contribute that leaves returning veterans Alex Green and James Starks as possible alternatives to Harris currently on the roster.