The temperature on Opening Day at Target Field could hover near the freezing mark, but the Twins can’t get on a plane to the Twin Cities fast enough as pitchers continue to drop by the wayside with aching body parts.

On Friday, righthander Cole De Vries left his start after three innings because of what was described as mild right forearm tightness. He left Hammond Stadium before meeting with reporters, so there is no sense of how bad he really feels. The Twins will wait until Saturday to see how De Vries, from Eden Prairie, is doing before they map a plan of action for the starting rotation.

The injury came on a day in which righthander Alex Burnett was claimed off waivers by the Toronto Blue Jays, and three days after would-be starter Liam Hendriks suffered a bruised right hand when it was struck by a line drive.

The injury also comes after reliever Tim Wood reported a mild rotator cuff strain. He remains sidelined.

And World Baseball Classic hero Samuel Deduno, another candidate for the rotation, remains sidelined because of a strained left groin.

The Twins were comfortable with what they considered starting pitching depth. Now they have a dearth of healthy starters.

Pitching coach Rick Anderson was at the minor league complex watching Anthony Swarzak throw when De Vries completed his third no-hit inning and walked into the dugout.

“He came to me and said he had a little tightness,” manager Ron Gardenhire said. “Right forearm tightness, and we’ll see [Saturday] how he is. I asked him if it was cramping, if it was barking. He said no, a little tightness. And the trainers took him in.