Shortly before Peyton Manning led the Denver Broncos onto the field Sunday night a photo of Andrew Luck flashed on the video boards at Lucas Oil Stadium.

"Indianapolis Colts Quarterback" it was captioned as if at least for this night some folks would need a reminder.

Yet for all the pregame hoopla and much deserved ovations for Manning upon his return to Indianapolis Luck was the better quarterback Sunday night and the Colts were the better team in Indianapolis' 39-33 win.

Luck threw for three touchdowns and rushed for another score and led the Colts to two fourth-quarter field goals to keep Manning's comeback bid at bay. Manning also threw an interception and running back Ronnie Hillman fumbled near the goal line to help the Colts maintain their fourth-quarter lead.

For the Broncos it was their first loss of the season and their first regular-season loss since Oct. 7 2012 a streak of 19 consecutive games.

Manning struggled like he hasn't all season after taking a big hit from former teammate Robert Mathis in the second quarter. Manning fumbled on the play resulting in a safety – and serious momentum – for the Colts who built a 26-14 lead by halftime.

It was hardly the type of homecoming Manning could have wanted especially after a drama-filled week thanks to comments Colts owner Jim Irsay made to USA TODAY Sports lamenting the Colts' lack of multiple Super Bowl titles during Manning's time in Indianapolis.