Mark Buehrle used the words "weird" and "crazy" to describe facing a White Sox team he was a member of for 12 memorable seasons.

Those words also fit the latest misfortunes of the Sox, who failed to deliver a knockout punch and fell to Buehrle and the Blue Jays 4-3 for their sixth loss in seven games on their 10-game trip.

As he did for most of his 161 wins with the Sox from 2000 to 2011, Buehrle relied on his crafty pitching to work out of jams. His signature moment occurred with two outs in the fifth inning when he struck out longtime friend Paul Konerko on a full count with two runners on base.

Konerko had hit an RBI single and lined to left in his first two at-bats but wasn't too happy about a 2-1 pitch on the outside corner that was called a strike by plate umpire Tony Randazzo.

"I had the at-bat I wanted to have," Konerko said. "I had a 2-1 pitch that was ... whatever. So sometimes you've got two choices. You stand up there and strike out looking, or you swing the bat on a pitch you don't want to swing at or don't have to. That's the moral of the story."

Buehrle told reporters: "Obviously you don't want to screw around there with runners on, and if something bad happens, it won't look good. I just kind of said to myself, 'Don't make eye contact with (Konerko), whether there's nobody on base or its bases loaded.'

"I obviously know how good of a hitter he is. You have to make some pitches there, so you have to keep the ball down on him."

Konerko admitted to feeling uncomfortable facing a friend and former teammate.

"I didn't have much fun with it, and I don't think he did, either," Konerko said.