Greg Zuerlein kicked a 48-yard field goal with 40 seconds remaining to give the Rams a 27-24 victory over the Arizona Cardinals in their NFL season opener at the Edward Jones Dome.

The game-winner was Zuerlein's fourth field goal and it gave the Rams their first victory in a season opener since 2006.

Tight end Jared Cook had two touchdown catches in his Rams debut. The tight end fumbled a potential third TD a 55-yarder that would have opened the scoring when rookie Tyrann Mathieu punched the ball free at the 8 and the play resulted in a touchback.

Larry Fitzgerald caught two touchdown passes from new quarterback Carson Palmer and the Arizona defense scored one touchdown.